Best Cannabis Dispensaries in Port Saint Lucie, FL (2026)

Updated April 2026

Port Saint Lucie, Florida has 19 dispensaries listed in our directory, giving medical cannabis consumers plenty of options to choose from. Whether you are a longtime local or visiting for the first time, this guide highlights the top-rated dispensaries in Port Saint Lucie based on verified customer reviews, ratings, and overall experience.

How We Ranked These Dispensaries

Our ranking methodology combines multiple data points to surface the dispensaries that consistently deliver the best customer experience:

• Verified customer ratings — We analyze star ratings from verified purchasers, filtering out shops with fewer than a handful of reviews.
• Review volume — A dispensary with thousands of reviews and a high star rating has proven itself more reliably than one with just a few reviews.
• Product selection and services — Shops that carry a wide variety of flower, concentrates, edibles, topicals, and accessories score higher.
• Location and accessibility — Convenient hours, parking, and accessibility matter.

We pulled real data from our directory of 19 dispensaries in the Port Saint Lucie area to compile this list. Every name, rating, review count, and address below comes directly from verified listings in the Budpedia dispensary directory.

Top 15 Cannabis Dispensaries in Port Saint Lucie (2026)

1. Trulieve Stuart Dispensary

Rating: 5 stars (15 reviews) Address: 1970 NW Federal HWY Phone: (772) 238-5035 Hours: 11:00 – 20:00 (hours vary)

Trulieve Stuart Dispensary earns a 5-star rating from its customers, making it one of the highest-rated options in Port Saint Lucie.

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2. Trulieve Port Saint Lucie Dispensary

Rating: 5 stars (5 reviews) Address: 1288 SW Gatlin Blvd. Phone: (772) 230-5370 Hours: 11:00 – 20:00 (hours vary)

Trulieve Port Saint Lucie Dispensary earns a 5-star rating from its customers, making it one of the highest-rated options in Port Saint Lucie.

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3. Sanctuary Cannabis - Fort Pierce

Rating: 5 stars (3 reviews) Address: 5001 S US-1 Phone: (772) 742-8783 Hours: 10:00 – 18:00 (hours vary)

Sanctuary Cannabis - Fort Pierce earns a 5-star rating from its customers, making it one of the highest-rated options in Port Saint Lucie.

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4. MÜV Dispensary Port St. Lucie

Rating: 5 stars (1 reviews) Address: 120 Chamber Ct Phone: (833) 880-5420 Hours: 11:00 – 17:00 (hours vary)

MÜV Dispensary Port St. Lucie earns a 5-star rating from its customers, making it one of the highest-rated options in Port Saint Lucie.

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5. Cookies Port St Lucie

Rating: 5 stars (1 reviews) Address: 1401 SE Village Green Dr. Suite B Phone: (772) 732-7205 Hours: 10:00 – 20:00 (hours vary)

Cookies Port St Lucie earns a 5-star rating from its customers, making it one of the highest-rated options in Port Saint Lucie.

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6. Surterra Wellness Center - Port St. Lucie

Rating: 5 stars (1 reviews) Address: 7061 S U.S. Hwy 1 Phone: (850) 391-5455 Hours: 11:00 – 18:00 (hours vary)

Surterra Wellness Center - Port St. Lucie earns a 5-star rating from its customers, making it one of the highest-rated options in Port Saint Lucie.

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7. Curaleaf - Port Saint Lucie

Rating: 5 stars (1 reviews) Address: 1720 Southwest Gatlin Boulevard Port Saint Lucie, FL 34953 Phone: (772) 261-3300 Hours: 10:00 – 19:00 (hours vary)

Curaleaf - Port Saint Lucie earns a 5-star rating from its customers, making it one of the highest-rated options in Port Saint Lucie.

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8. Trulieve Fort Pierce Dispensary

Rating: 5 stars (1 reviews) Address: 1495 S US Hwy 1 Phone: (772) 230-4730 Hours: 11:00 – 20:00 (hours vary)

Trulieve Fort Pierce Dispensary earns a 5-star rating from its customers, making it one of the highest-rated options in Port Saint Lucie.

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9. Curaleaf - Jensen Beach

Rating: 4.6 stars (10 reviews) Address: 3631 NW Federal Hwy Phone: (772) 934-9575 Hours: 10:00 – 19:00 (hours vary)

Curaleaf - Jensen Beach earns a 4.6-star rating from its customers, making it one of the highest-rated options in Port Saint Lucie.

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10. Sanctuary Cannabis - Tampa

Rating: 4.6 stars (10 reviews) Address: 5001 S US-1 Phone: (813) 443-0787 Hours: 10:00 – 18:00 (hours vary)

Sanctuary Cannabis - Tampa earns a 4.6-star rating from its customers, making it one of the highest-rated options in Port Saint Lucie.

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11. Curaleaf - Ft. Pierce

Rating: 4.2 stars (12 reviews) Address: 3218 S. US Highway 1 Phone: (772) 577-7762 Hours: 10:00 – 18:00 (hours vary)

Curaleaf - Ft. Pierce serves the Port Saint Lucie community with a range of medical cannabis products. Deals and Discounts available daily, check our online menu on our website for the most up to date deals & discounts.

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12. FLUENT - Fort Pierce

Rating: 4.2 stars (12 reviews) Address: 2620 South US Highway 1 Phone: (833) 735-8368 Hours: Daily 09:00 – 20:30

FLUENT - Fort Pierce serves the Port Saint Lucie community with a range of medical cannabis products.

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13. Sunnyside Medical Cannabis Dispensary - Port St. Lucie

Rating: 3.7 stars (3 reviews) Address: 7510 South Federal Hwy Phone: (772) 207-3322 Hours: 09:00 – 18:00 (hours vary)

Sunnyside Medical Cannabis Dispensary - Port St. Lucie serves the Port Saint Lucie community with a range of medical cannabis products.

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14. AYR Cannabis Dispensary Port St. Lucie

Rating: 3.2 stars (48 reviews) Address: 10941 US Highway 1 Phone: (772) 249-4199 Hours: 10:00 – 20:00 (hours vary)

AYR Cannabis Dispensary Port St. Lucie serves the Port Saint Lucie community with a range of medical cannabis products.

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15. MÜV Dispensary Fort Pierce

Rating: N/A stars (N/A reviews) Address: 1006 S US Hwy 1 Phone: (833) 880-5420 Hours: 11:00 – 17:00 (hours vary)

MÜV Dispensary Fort Pierce serves the Port Saint Lucie community with a range of medical cannabis products.

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Tips for Visiting Dispensaries in Port Saint Lucie

Bring valid ID. All dispensaries in Port Saint Lucie require a valid government-issued photo ID proving you are 21 or older for all purchases. A driver's license, state ID, or passport all work. Medical patients should bring their doctor's recommendation or state-issued medical marijuana card.

Check payment options ahead of time. Many cannabis dispensaries still operate primarily in cash due to federal banking restrictions. However, an increasing number now accept debit cards, and some accept credit cards with a small processing fee. Most dispensaries have ATMs on-site, but bringing cash avoids any hassle.

Take advantage of first-time customer deals. Nearly every dispensary offers a first-time visitor discount, typically 10–20% off your entire order. Some shops also offer loyalty programs that reward repeat visits. Ask about these deals before you check out.

Order online for pickup. Many of the dispensaries on this list offer online ordering for pickup, which lets you browse the menu at your own pace and skip the in-store wait. Check the dispensary's website or Budpedia listing for online ordering availability.

Ask your budtender for recommendations. Budtenders are knowledgeable about terpene profiles, consumption methods, and product effects. Whether you are a first-time consumer or looking for something specific, do not hesitate to ask. A good budtender can save you time and money.

For more guidance, check out our first-time dispensary visit guide.

Frequently Asked Questions

Is cannabis legal in Port Saint Lucie, FL?

Florida has legalized medical cannabis since 2016. Patients need a valid medical marijuana card or doctor's recommendation to purchase from dispensaries. Some dispensaries may also carry CBD products available without a medical card. Check individual listings for specific requirements.

What do I need to buy cannabis in Port Saint Lucie?

You need a valid government-issued photo ID showing you are at least 21 years old. Accepted forms include a state driver's license, state ID card, U.S. passport, or military ID. Medical patients will need a valid doctor's recommendation or state-issued medical marijuana identification card.

How many dispensaries are in Port Saint Lucie?

Port Saint Lucie has 19 dispensaries listed in the Budpedia directory. Browse all of them on our Port Saint Lucie city page.

Do Port Saint Lucie dispensaries offer delivery?

Many dispensaries in Port Saint Lucie offer delivery services, and some operate delivery-only models. Check individual dispensary listings on Budpedia for delivery availability and minimum order amounts.

Explore More Dispensaries in Port Saint Lucie

This list highlights the top 15, but Port Saint Lucie has 19 dispensaries to explore. Browse the full list on our Port Saint Lucie dispensaries page, or explore dispensaries by type on our dispensaries category page.

Are you a dispensary owner in Port Saint Lucie looking to reach more customers? Learn about advertising on Budpedia and get your shop in front of thousands of cannabis consumers searching for the best dispensaries in Port Saint Lucie.

Why It Matters: Find the best cannabis dispensaries in Port Saint Lucie, FL. Our 2026 guide ranks the top-rated dispensaries based on 123 verified reviews.